Long-term Safety of Dichloroacetate in Congenital Lactic Acidosis

We followed 8 patients (4 males) with biochemically and/or molecular genetically proven deficiencies of the E1α subunit of the pyruvate dehydrogenase complex (PDC; 3 patients) or respiratory chain complexes I (1 patient), IV (3 patients) or I+IV (1 patient) who received oral dichloroacetate (DCA; 12...

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Detalhes bibliográficos
Main Authors: Abdelmalak, Monica, Lew, Alicia, Ramezani, Ryan, Shroads, Albert L., Coats, Bonnie S., Langaee, Taimour, Shankar, Meena N., Neiberger, Richard E., Subramony, S.H., Stacpoole, Peter W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3751427/
https://ncbi.nlm.nih.gov/pubmed/23611579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymgme.2013.03.019
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