Effectivity of pazopanib treatment in orthotopic models of human testicular germ cell tumors

BACKGROUND: Cisplatin (CDDP) resistance in testicular germ cell tumors (GCTs) is still a clinical challenge, and one associated with poor prognosis. The purpose of this work was to test pazopanib, an anti-tumoral and anti-angiogenic multikinase inhibitor, and its combination with lapatinib (an anti-...

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Main Authors: Juliachs, Mercè, Vidal, August, del Muro, Xavier Garcia, Piulats, Josep M, Condom, Enric, Casanovas, Oriol, Graupera, Mariona, Germà, Jose R, Villanueva, Alberto, Viñals, Francesc
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2013
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Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3751347/
https://ncbi.nlm.nih.gov/pubmed/23937707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-13-382
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