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DNA vaccines targeting the encoded antigens to dendritic cells induce potent antitumor immunity in mice

BACKGROUND: Although DNA vaccine holds a great potential for cancer immunotherapy, effective long-lasting antitumoral immunity sufficient to induce durable responses in cancer patients remains to be achieved. Considering the pivotal role of dendritic cells (DC) in the antigen processing and presenta...

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Detalhes bibliográficos
Main Authors: Cao, Jun, Jin, Yiqi, Li, Wei, Zhang, Bin, He, Yang, Liu, Hongqiang, Xia, Ning, Wei, Huafeng, Yan, Jian
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3751307/
https://ncbi.nlm.nih.gov/pubmed/23941509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2172-14-39
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