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Lung effector memory and activated CD4+ T cells display enhanced proliferation in SP-A-deficient mice during allergen-mediated inflammation

Although many studies show that pulmonary Surfactant Protein A (SP-A) functions in innate immunity, fewer studies have addressed its role in adaptive immunity and allergic hypersensitivity. We hypothesized that SP-A modulates the phenotype and prevalence of dendritic cells (DCs) and CD4+ T cells to...

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Autors principals: Pastva, Amy M., Mukherjee, Sambuddho, Giamberardino, Charles, Hsia, Bethany, Lo, Bernice, Sempowski, Gregory D., Wright, Jo Rae
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3750987/
https://ncbi.nlm.nih.gov/pubmed/21257967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0904190
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