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Methods in Enzymology: “Flexible backbone sampling methods to model and design protein alternative conformations”
Sampling alternative conformations is key to understanding how proteins work and engineering them for new functions. However, accurately characterizing and modeling protein conformational ensembles remains experimentally and computationally challenging. These challenges must be met before protein co...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3750959/ https://ncbi.nlm.nih.gov/pubmed/23422426 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/B978-0-12-394292-0.00004-7 |
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