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Methods in Enzymology: “Flexible backbone sampling methods to model and design protein alternative conformations”

Sampling alternative conformations is key to understanding how proteins work and engineering them for new functions. However, accurately characterizing and modeling protein conformational ensembles remains experimentally and computationally challenging. These challenges must be met before protein co...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Ollikainen, Noah, Smith, Colin A., Fraser, James S., Kortemme, Tanja
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2013
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3750959/
https://ncbi.nlm.nih.gov/pubmed/23422426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/B978-0-12-394292-0.00004-7
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