Role of reactive oxygen species (ROS) in CDDO-Me-mediated growth inhibition and apoptosis in colorectal cancer cells

CDDO-Me, an oleanane synthetic triterpenoid has shown strong antitumorigeic activity towards diverse cancer cell types including colorectal cancer cells. In the present study, we investigated the role of free radicals in the growth inhibitory and apoptosis-inducing activity of CDDO-Me in colorectal...

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Main Authors: Gao, Xiaohua, Deeb, Dorrah, Liu, Patricia, Liu, Yongbo, Arbab-Ali, Syed, Dulchavsky, Scott A., Gautam, Subhash C.
Format: Artigo
Jezik:Inglês
Izdano: 2011
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3750951/
https://ncbi.nlm.nih.gov/pubmed/21699019
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