A germ-line Tsc1 mutation causes tumor development and embryonic lethality that are similar, but not identical to, those caused by Tsc2 mutation in mice

Tuberous sclerosis (TS) is characterized by the development of hamartomas in various organs and is caused by a germ-line mutation in either TSC1 or TSC2 tumor suppressor genes. From the symptomatic resemblance among TS patients, involvement of TSC1 and TSC2 products in a common pathway has been sugg...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Kobayashi, Toshiyuki, Minowa, Osamu, Sugitani, Yoshinobu, Takai, Setsuo, Mitani, Hiroaki, Kobayashi, Etsuko, Noda, Tetsuo, Hino, Okio
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2001
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC37509/
https://ncbi.nlm.nih.gov/pubmed/11438694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.151033798
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados