Intragenic Tsc2 Somatic Mutations as Knudson's Second Hit in Spontaneous and Chemically Induced Renal Carcinomas in the Eker Rat Model

We searched for the rat homologue of the human tuberous sclerosis (TSC2) gene mutations in loss of heterozygosity (LOH)‐negative Eker rat renal carcinomas (RCs) by polymerase chain reactionsingle‐strand conformational polymorphism (PCR‐SSCP) analysis using 45 primer sets covering all 41 coding exons...

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Bibliografiske detaljer
Udgivet i:Jpn J Cancer Res
Main Authors: Kobayashi, Toshiyuki, Urakami, Shinji, Hirayama, Youko, Yamamoto, Toshiki, Nishizawa, Masae, Takahara, Tomoko, Kubo, Yoshiaki, Hino, Okio
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Publishing Ltd 1997
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5921374/
https://ncbi.nlm.nih.gov/pubmed/9140109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1997.tb00375.x
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