Intragenic Tsc2 Somatic Mutations as Knudson's Second Hit in Spontaneous and Chemically Induced Renal Carcinomas in the Eker Rat Model

We searched for the rat homologue of the human tuberous sclerosis (TSC2) gene mutations in loss of heterozygosity (LOH)‐negative Eker rat renal carcinomas (RCs) by polymerase chain reactionsingle‐strand conformational polymorphism (PCR‐SSCP) analysis using 45 primer sets covering all 41 coding exons...

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Vydáno v:Jpn J Cancer Res
Hlavní autoři: Kobayashi, Toshiyuki, Urakami, Shinji, Hirayama, Youko, Yamamoto, Toshiki, Nishizawa, Masae, Takahara, Tomoko, Kubo, Yoshiaki, Hino, Okio
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Publishing Ltd 1997
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5921374/
https://ncbi.nlm.nih.gov/pubmed/9140109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1997.tb00375.x
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