Identification of a Novel Indoline Derivative for in Vivo Fluorescent Imaging of Blood-Brain Barrier Disruption in Animal Models

[Image: see text] Disruption of the blood-brain barrier (BBB) can occur in various pathophysiological conditions. Administration of extraneous tracers that can pass the disrupted, but not the intact, BBB and detection of the extravasation have been widely used to assess BBB disruption in animal mode...

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Hoofdauteurs: Nishimura, Yuhei, Yata, Kenichiro, Nomoto, Tsuyoshi, Ogiwara, Tomoaki, Watanabe, Kohei, Shintou, Taichi, Tsuboyama, Akira, Okano, Mie, Umemoto, Noriko, Zhang, Zi, Kawabata, Miko, Zhang, Beibei, Kuroyanagi, Junya, Shimada, Yasuhito, Miyazaki, Takeshi, Imamura, Takeshi, Tomimoto, Hidekazu, Tanaka, Toshio
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Chemical Society 2013
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3750685/
https://ncbi.nlm.nih.gov/pubmed/23668665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cn400010t
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