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Quantitative Phenotyping-Based In Vivo Chemical Screening in a Zebrafish Model of Leukemia Stem Cell Xenotransplantation

Zebrafish-based chemical screening has recently emerged as a rapid and efficient method to identify important compounds that modulate specific biological processes and to test the therapeutic efficacy in disease models, including cancer. In leukemia, the ablation of leukemia stem cells (LSCs) is nec...

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Detalhes bibliográficos
Main Authors: Zhang, Beibei, Shimada, Yasuhito, Kuroyanagi, Junya, Umemoto, Noriko, Nishimura, Yuhei, Tanaka, Toshio
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3893211/
https://ncbi.nlm.nih.gov/pubmed/24454867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0085439
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