CCR7 signalling as an essential regulator of CNS infiltration in T-cell leukaemia

T-cell acute lymphoblastic leukaemia (T-ALL) is a blood malignancy afflicting mainly children and adolescents(1). T-ALL patients present at diagnosis with increased white cell counts and hepatosplenomegaly, and are at an increased risk of central nervous system (CNS) relapse(2,3). For that reason, T...

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Detalhes bibliográficos
Main Authors: Buonamici, Silvia, Trimarchi, Thomas, Ruocco, Maria Grazia, Reavie, Linsey, Cathelin, Severine, Mar, Brenton G., Klinakis, Apostolos, Lukyanov, Yevgeniy, Tseng, Jen-Chieh, Sen, Filiz, Gehrie, Eric, Li, Mengling, Newcomb, Elizabeth, Zavadil, Jiri, Meruelo, Daniel, Lipp, Martin, Ibrahim, Sherif, Efstratiadis, Argiris, Zagzag, David, Bromberg, Jonathan S., Dustin, Michael L., Aifantis, Iannis
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3750496/
https://ncbi.nlm.nih.gov/pubmed/19536265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature08020
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