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Igf1r as a therapeutic target in a mouse model of basal-like breast cancer

Considering the strong association between dysregulated insulin-like growth factor (IGF) signaling and various human cancers, we have used an expedient combination of genetic analysis and pharmacological treatment to evaluate the potential of the type 1 IGF receptor (Igf1r) for targeted anticancer t...

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Détails bibliographiques
Auteurs principaux: Klinakis, Apostolos, Szabolcs, Matthias, Chen, Guoying, Xuan, Shouhong, Hibshoosh, Hanina, Efstratiadis, Argiris
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2650161/
https://ncbi.nlm.nih.gov/pubmed/19174523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0810221106
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