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Regulation of hematopoietic stem cell fate by the ubiquitin proteasome system

Hematopoietic stem cells (HSCs) residing in the bone marrow generate mature blood cells throughout the life of the organism. This is accomplished by careful regulation of HSC activity to balance quiescence, self-renewal and differentiation. Studies of the molecular mechanisms governing HSC maintenan...

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Autori principali: Crusio, Kelly M., Reavie, Linsey B., Aifantis, Iannis
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3694760/
https://ncbi.nlm.nih.gov/pubmed/22349458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.it.2012.01.009
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