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Estimating DNA polymorphism from next generation sequencing data with high error rate by dual sequencing applications
BACKGROUND: As the error rate is high and the distribution of errors across sites is non-uniform in next generation sequencing (NGS) data, it has been a challenge to estimate DNA polymorphism (θ) accurately from NGS data. RESULTS: By computer simulations, we compare the two methods of data acquisiti...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3750404/ https://ncbi.nlm.nih.gov/pubmed/23919637 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-14-535 |
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