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Synonymous site conservation in the HIV-1 genome

BACKGROUND: Synonymous or silent mutations are usually thought to evolve neutrally. However, accumulating recent evidence has demonstrated that silent mutations may destabilize RNA structures or disrupt cis regulatory motifs superimposed on coding sequences. Such observations suggest the existence o...

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書誌詳細
主要な著者: Mayrose, Itay, Stern, Adi, Burdelova, Ela O, Sabo, Yosef, Laham-Karam, Nihay, Zamostiano, Rachel, Bacharach, Eran, Pupko, Tal
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3750384/
https://ncbi.nlm.nih.gov/pubmed/23914950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2148-13-164
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