Synonymous site conservation in the HIV-1 genome

BACKGROUND: Synonymous or silent mutations are usually thought to evolve neutrally. However, accumulating recent evidence has demonstrated that silent mutations may destabilize RNA structures or disrupt cis regulatory motifs superimposed on coding sequences. Such observations suggest the existence o...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Mayrose, Itay, Stern, Adi, Burdelova, Ela O, Sabo, Yosef, Laham-Karam, Nihay, Zamostiano, Rachel, Bacharach, Eran, Pupko, Tal
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2013
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3750384/
https://ncbi.nlm.nih.gov/pubmed/23914950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2148-13-164
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