Synonymous site conservation in the HIV-1 genome

BACKGROUND: Synonymous or silent mutations are usually thought to evolve neutrally. However, accumulating recent evidence has demonstrated that silent mutations may destabilize RNA structures or disrupt cis regulatory motifs superimposed on coding sequences. Such observations suggest the existence o...

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Detalhes bibliográficos
Main Authors: Mayrose, Itay, Stern, Adi, Burdelova, Ela O, Sabo, Yosef, Laham-Karam, Nihay, Zamostiano, Rachel, Bacharach, Eran, Pupko, Tal
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3750384/
https://ncbi.nlm.nih.gov/pubmed/23914950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2148-13-164
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