Prolylcarboxypeptidase promotes angiogenesis and vascular repair

Prolylcarboxypeptidase (PRCP) is associated with leanness, hypertension, and thrombosis. PRCP-depleted mice have injured vessels with reduced Kruppel-like factor (KLF)2, KLF4, endothelial nitric oxide synthase (eNOS), and thrombomodulin. Does PRCP influence vessel growth, angiogenesis, and injury re...

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Autori principali: Adams, Gregory N., Stavrou, Evi X., Fang, Chao, Merkulova, Alona, Alaiti, M. Amer, Nakajima, Kohsuke, Morooka, Toshifumi, Merkulov, Sergei, LaRusch, Gretchen A., Simon, Daniel I, Jain, Mukesh K., Schmaier, Alvin H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2013
Soggetti:
Vascular Biology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3750346/
https://ncbi.nlm.nih.gov/pubmed/23744584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-10-460360
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