Inflammasome activation mediates inflammation and outcome in humans and mice with pneumococcal meningitis

BACKGROUND: Inflammasomes are multi-protein intracellular signaling complexes that have recently been hypothesized to play a role in the regulation of the inflammation response. We studied associations between inflammasome-associated cytokines IL-1β and IL-18 in cerebrospinal fluid (CSF) of patients...

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Detalhes bibliográficos
Main Authors: Geldhoff, Madelijn, Mook-Kanamori, Barry B, Brouwer, Matthijs C, Troost, Dirk, Leemans, Jaklien C, Flavell, Richard A, Van der Ende, Arie, Van der Poll, Tom, Van de Beek, Diederik
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3750264/
https://ncbi.nlm.nih.gov/pubmed/23902681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2334-13-358
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