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Characterization of a pneumococcal meningitis mouse model

BACKGROUND: S. pneumoniae is the most common causative agent of meningitis, and is associated with high morbidity and mortality. We aimed to develop an integrated and representative pneumococcal meningitis mouse model resembling the human situation. METHODS: Adult mice (C57BL/6) were inoculated in t...

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Detalhes bibliográficos
Main Authors: Mook-Kanamori, Barry, Geldhoff, Madelijn, Troost, Dirk, van der Poll, Tom, van de Beek, Diederik
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3364848/
https://ncbi.nlm.nih.gov/pubmed/22455545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2334-12-71
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