Differential Effects of Mutations on the Transport Properties of the Na(+)/H(+) Antiporter NhaA from Escherichia coli

Na(+)/H(+) antiporters show a marked pH dependence, which is important for their physiological function in eukaryotic and prokaryotic cells. In NhaA, the Escherichia coli Na(+)/H(+) antiporter, specific single site mutations modulating the pH profile of the transporter have been described in the pas...

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Main Authors: Mager, Thomas, Braner, Markus, Kubsch, Bastian, Hatahet, Lina, Alkoby, Dudu, Rimon, Abraham, Padan, Etana, Fendler, Klaus
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2013
Teme:
Molecular Biophysics
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3750164/
https://ncbi.nlm.nih.gov/pubmed/23836890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.484071
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