Potential role of CYP2D6 in the central nervous system

1. Cytochrome P450 2D6 (CYP2D6) is a pivotal enzyme responsible for a major human drug oxidation polymorphism in human populations. Distribution of CYP2D6 in brain and its role in serotonin metabolism suggest this CYP2D6 may have a function in central nervous system. 2. To establish an efficient and...

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Détails bibliographiques
Auteurs principaux: Cheng, Jie, Zhen, Yueying, Miksys, Sharon, Beyoğlu, Diren, Krausz, Kristopher W., Tyndale, Rachel F., Yu, Aiming, Idle, Jeffrey R., Gonzalez, Frank J.
Format: Artigo
Langue:Inglês
Publié: 2013
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3750078/
https://ncbi.nlm.nih.gov/pubmed/23614566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/00498254.2013.791410
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