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The Natural Product Honokiol Inhibits Calcineurin Inhibitor-induced and Ras-mediated Tumor Promoting Pathways
Although calcineurin inhibitors (CNIs) are very useful in preventing allograft rejection, they can mediate a rapid progression of post-transplantation malignancies. The CNI cyclosporine A (CsA) can promote renal tumor growth through activation of the proto-oncogene ras and over-expression of the ang...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3750070/ https://ncbi.nlm.nih.gov/pubmed/23752066 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2013.05.036 |
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