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CD70 is downregulated by interaction with CD27
Engagement of the receptor CD27 by CD70 affects the magnitude and quality of T cell responses in a variety of infection models, and exaggerated signaling via this pathway results in enhanced immune responses and autoimmunity. One means by which signaling is regulated is tight control of cell surface...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3750068/ https://ncbi.nlm.nih.gov/pubmed/23913967 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1300868 |
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