Candidate Gene Analysis of Tooth Agenesis Identifies Novel Mutations in Six Genes and Suggests Significant Role for WNT and EDA Signaling and Allele Combinations

Failure to develop complete dentition, tooth agenesis, is a common developmental anomaly manifested most often as isolated but also as associated with many developmental syndromes. It typically affects third molars or one or few other permanent teeth but severe agenesis is also relatively prevalent....

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Bibliographic Details
Main Authors: Arte, Sirpa, Parmanen, Satu, Pirinen, Sinikka, Alaluusua, Satu, Nieminen, Pekka
Format: Artigo
Language:Inglês
Published: Public Library of Science 2013
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3750013/
https://ncbi.nlm.nih.gov/pubmed/23991204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0073705
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