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Candidate Gene Analysis of Tooth Agenesis Identifies Novel Mutations in Six Genes and Suggests Significant Role for WNT and EDA Signaling and Allele Combinations

Failure to develop complete dentition, tooth agenesis, is a common developmental anomaly manifested most often as isolated but also as associated with many developmental syndromes. It typically affects third molars or one or few other permanent teeth but severe agenesis is also relatively prevalent....

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Autors principals: Arte, Sirpa, Parmanen, Satu, Pirinen, Sinikka, Alaluusua, Satu, Nieminen, Pekka
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3750013/
https://ncbi.nlm.nih.gov/pubmed/23991204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0073705
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