Mutations in AXIN2 Cause Familial Tooth Agenesis and Predispose to Colorectal Cancer

Wnt signaling regulates embryonic pattern formation and morphogenesis of most organs. Aberrations of regulation of Wnt signaling may lead to cancer. Here, we have used positional cloning to identify the causative mutation in a Finnish family in which severe permanent tooth agenesis (oligodontia) and...

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Detaylı Bibliyografya
Asıl Yazarlar: Lammi, Laura, Arte, Sirpa, Somer, Mirja, Järvinen, Heikki, Lahermo, Päivi, Thesleff, Irma, Pirinen, Sinikka, Nieminen, Pekka
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The American Society of Human Genetics 2004
Konular:
Report
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1181967/
https://ncbi.nlm.nih.gov/pubmed/15042511
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