Structure of Protein Related to DAN and Cerberus (PRDC): Insights into the Mechanism of BMP Antagonism

The Bone Morphogenetic Proteins (BMP) are secreted ligands largely known for their functional roles in embryogenesis and tissue development. A number of structurally diverse extracellular antagonists inhibit BMP ligands to regulate signaling. The DAN family of antagonists represents the largest grou...

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Bibliografiske detaljer
Main Authors: Nolan, Kristof, Kattamuri, Chandramohan, Luedeke, David M., Deng, Andy, Jagpal, Amrita, Zhang, Fuming, Linhardt, Robert, Kenny, Alan P., Zorn, Aaron M., Thompson, Thomas B.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3749838/
https://ncbi.nlm.nih.gov/pubmed/23850456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2013.06.005
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