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Members of the DAN Family are BMP Antagonists that form Highly Stable Noncovalent Dimers

Signaling of BMP ligands is antagonized by a number of extracellular proteins, including noggin, follistatin and members of the DAN family. Structural studies on the DAN family member sclerostin (a weak BMP antagonist) have previously revealed that the protein is monomeric and consists of an 8-membe...

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Detalhes bibliográficos
Main Authors: Kattamuri, Chandramohan, Luedeke, David M., Nolan, Kristof, Rankin, Scott A., Greis, Kenneth D., Zorn, Aaron M., Thompson, Thomas B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3509953/
https://ncbi.nlm.nih.gov/pubmed/23063586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2012.10.003
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