Intercellular Coupling Confers Robustness against Mutations in the SCN Circadian Clock Network

Molecular mechanisms of the mammalian circadian clock have been studied primarily by genetic perturbation and behavioral analysis. Here, we used bioluminescence imaging to monitor Per2 gene expression in tissues and cells from clock mutant mice. We discovered that Per1 and Cry1 are required for sust...

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Библиографические подробности
Главные авторы: Liu, Andrew C., Welsh, David K., Ko, Caroline H., Tran, Hien G., Zhang, Eric E., Priest, Aaron A., Buhr, Ethan D., Singer, Oded, Meeker, Kirsten, Verma, Inder M., Doyle III, Francis J., Takahashi, Joseph S., Kay, Steve A.
Формат: Artigo
Язык:Inglês
Опубликовано: 2007
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3749832/
https://ncbi.nlm.nih.gov/pubmed/17482552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2007.02.047
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