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Robustness properties of circadian clock architectures

Robustness, a relative insensitivity to perturbations, is a key characteristic of living cells. However, the specific structural characteristics that are responsible for robust performance are not clear, even in genetic circuits of moderate complexity. Formal sensitivity analysis allows the investig...

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Detalhes bibliográficos
Main Authors: Stelling, Jörg, Gilles, Ernst Dieter, Doyle, Francis J.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC516549/
https://ncbi.nlm.nih.gov/pubmed/15340155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0401463101
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