Growth Hormone Potentiates 17β-Estradiol-Dependent Breast Cancer Cell Proliferation Independently of IGF-I Receptor Signaling

Estrogen action in mammary gland development and breast cancer progression is tightly linked to the GH/IGF-I axis. Although many of the effects of GH on mammary gland growth and development require IGF-I, the extent to which GH action in breast cancer depends on IGF-I is not known. We examined GH ac...

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Bibliographische Detailangaben
Hauptverfasser: Felice, Dana L., El-Shennawy, Lamiaa, Zhao, Shuangping, Lantvit, Daniel L., Shen, Qi, Unterman, Terry G., Swanson, Steven M., Frasor, Jonna
Format: Artigo
Sprache:Inglês
Veröffentlicht: Endocrine Society 2013
Schlagworte:
Growth Hormone-Somatostatin-GRH
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3749474/
https://ncbi.nlm.nih.gov/pubmed/23782942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2012-2208
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