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Increased Brain Lactate Concentrations Without Increased Lactate Oxidation During Hypoglycemia in Type 1 Diabetic Individuals

Previous studies have reported that brain metabolism of acetate is increased more than twofold during hypoglycemia in type 1 diabetic (T1D) subjects with hypoglycemia unawareness. These data support the hypothesis that upregulation of blood-brain barrier monocarboxylic acid (MCA) transport may contr...

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Detalhes bibliográficos
Main Authors: De Feyter, Henk M., Mason, Graeme F., Shulman, Gerald I., Rothman, Douglas L., Petersen, Kitt Falk
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3749358/
https://ncbi.nlm.nih.gov/pubmed/23715622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db13-0313
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