Rescue of a Wnt mutation by an activated form of LEF-1: Regulation of maintenance but not initiation of Brachyury expression

Members of the LEF-1/TCF family of transcription factors have been implicated in mediating a nuclear response to Wnt signals by association with β-catenin. Consistent with this view, mice carrying mutations in either the Wnt3a gene or in both transcription factor genes Lef1 and Tcf1 were previously...

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Bibliografische Detailangaben

Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Galceran, Juan, Hsu, Shu-Chi, Grosschedl, Rudolf
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 2001
Schlagworte:	Biological Sciences
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC37493/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11447280/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.151258098
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