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Hypomethylation of Alu Elements in Post-Menopausal Women with Osteoporosis
A decrease in genomic methylation commonly occurs in aging cells; however, whether this epigenetic modification leads to age-related phenotypes has not been evaluated. Alu elements are the major interspersed repetitive DNA elements in humans that lose DNA methylation in aging individuals. Alu demeth...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3749148/ https://ncbi.nlm.nih.gov/pubmed/23990903 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0070386 |
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