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Hypomethylation of Alu Elements in Post-Menopausal Women with Osteoporosis

A decrease in genomic methylation commonly occurs in aging cells; however, whether this epigenetic modification leads to age-related phenotypes has not been evaluated. Alu elements are the major interspersed repetitive DNA elements in humans that lose DNA methylation in aging individuals. Alu demeth...

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Main Authors: Jintaridth, Pornrutsami, Tungtrongchitr, Rungsunn, Preutthipan, Sangchai, Mutirangura, Apiwat
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3749148/
https://ncbi.nlm.nih.gov/pubmed/23990903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0070386
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