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Systemic Administration of Sclerostin Antibody Enhances Bone Repair in a Critical-Sized Femoral Defect in a Rat Model

BACKGROUND: Systemic administration of sclerostin neutralizing antibody has led to increased bone formation in animal models of osteoporosis. The purpose of this study was to determine if systemic administration of sclerostin neutralizing antibody could increase the healing response in a critical-si...

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Detalles Bibliográficos
Main Authors: Virk, Mandeep S., Alaee, Farhang, Tang, Hezhen, Ominsky, Michael S., Ke, Hua Zhu, Lieberman, Jay R.
Formato: Artigo
Idioma:Inglês
Publicado: Journal of Bone and Joint Surgery, Inc. 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3748979/
https://ncbi.nlm.nih.gov/pubmed/23595067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2106/JBJS.L.00285
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