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Systemic Administration of Sclerostin Antibody Enhances Bone Repair in a Critical-Sized Femoral Defect in a Rat Model

BACKGROUND: Systemic administration of sclerostin neutralizing antibody has led to increased bone formation in animal models of osteoporosis. The purpose of this study was to determine if systemic administration of sclerostin neutralizing antibody could increase the healing response in a critical-si...

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Bibliografski detalji
Glavni autori: Virk, Mandeep S., Alaee, Farhang, Tang, Hezhen, Ominsky, Michael S., Ke, Hua Zhu, Lieberman, Jay R.
Format: Artigo
Jezik:Inglês
Izdano: Journal of Bone and Joint Surgery, Inc. 2013
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3748979/
https://ncbi.nlm.nih.gov/pubmed/23595067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2106/JBJS.L.00285
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