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Systemic Administration of Sclerostin Antibody Enhances Bone Repair in a Critical-Sized Femoral Defect in a Rat Model

BACKGROUND: Systemic administration of sclerostin neutralizing antibody has led to increased bone formation in animal models of osteoporosis. The purpose of this study was to determine if systemic administration of sclerostin neutralizing antibody could increase the healing response in a critical-si...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Virk, Mandeep S., Alaee, Farhang, Tang, Hezhen, Ominsky, Michael S., Ke, Hua Zhu, Lieberman, Jay R.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Journal of Bone and Joint Surgery, Inc. 2013
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3748979/
https://ncbi.nlm.nih.gov/pubmed/23595067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2106/JBJS.L.00285
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