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Negative control of mast cell degranulation and the anaphylactic response by the phosphatase lipin1

Mast cells play a critical role in the pathogenesis of allergic diseases. How mast cell function is regulated is still not well understood. Both phosphatidic acid (PA) and diacylglycerol (DAG) are important second messengers involved in mast cell activation. Lipin1 is a phosphatidate phosphatase tha...

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Detalhes bibliográficos
Main Authors: Shin, Jinwook, Zhang, Ping, Wang, Shang, Wu, Jinhong, Guan, Ziqiang, Zhong, Xiao-Ping
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3748934/
https://ncbi.nlm.nih.gov/pubmed/23065777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201242571
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