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Regulation of mast cell survival and function by tuberous sclerosis complex 1
Mast cells play critical roles in allergic disorders and asthma. The importance of tuberous sclerosis complex 1/2-mammalian target of rapamycin (TSC1/2-mTOR) signaling in mast cells is unknown. Here, we report that TSC1 is a critical regulator for mTOR signaling in mast cells downstream of FcεRI and...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society of Hematology
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3321856/ https://ncbi.nlm.nih.gov/pubmed/22362037 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-05-353342 |
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