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Regulation of mast cell survival and function by tuberous sclerosis complex 1

Mast cells play critical roles in allergic disorders and asthma. The importance of tuberous sclerosis complex 1/2-mammalian target of rapamycin (TSC1/2-mTOR) signaling in mast cells is unknown. Here, we report that TSC1 is a critical regulator for mTOR signaling in mast cells downstream of FcεRI and...

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Detalhes bibliográficos
Main Authors: Shin, Jinwook, Pan, Hongjie, Zhong, Xiao-Ping
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3321856/
https://ncbi.nlm.nih.gov/pubmed/22362037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-05-353342
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