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Celecoxib enhances radiosensitivity of hypoxic glioblastoma cells through endoplasmic reticulum stress
BACKGROUND: Refractoriness of glioblastoma multiforme (GBM) largely depends on its radioresistance. We investigated the radiosensitizing effects of celecoxib on GBM cell lines under both normoxic and hypoxic conditions. METHODS: Two human GBM cell lines, U87MG and U251MG, and a mouse GBM cell line,...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3748914/ https://ncbi.nlm.nih.gov/pubmed/23658321 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/not062 |
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