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Substrates and Controls for the Quantitative Detection of Active Botulinum Neurotoxin in Protease-containing Samples

Botulinum neurotoxins (BoNTs) are used in a wide variety of medical applications, but there is limited pharmacokinetic data on active BoNT. Monitoring BoNT activity in the circulation is challenging because BoNTs are highly toxic and are rapidly taken up by neurons and removed from the bloodstream....

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Detalhes bibliográficos
Main Authors: Bagramyan, Karine, Kaplan, Bruce E., Cheng, Luisa W., Strotmeier, Jasmin, Rummel, Andreas, Kalkum, Markus
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3748743/
https://ncbi.nlm.nih.gov/pubmed/23656526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac4008418
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