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Botulinum neurotoxin is shielded by NTNHA in an interlocked complex

Botulinum neurotoxins (BoNTs) are highly poisonous substances that are also effective medicines. Accidental BoNT poisoning often occurs through ingestion of Clostridium botulinum-contaminated food. Here, we present the crystal structure of a BoNT in complex with a clostridial non-toxic non-hemagglut...

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Detalhes bibliográficos
Main Authors: Gu, Shenyan, Rumpel, Sophie, Zhou, Jie, Strotmeier, Jasmin, Bigalke, Hans, Perry, Kay, Shoemaker, Charles B., Rummel, Andreas, Jin, Rongsheng
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3545708/
https://ncbi.nlm.nih.gov/pubmed/22363010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1214270
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