Structure of a Bimodular Botulinum Neurotoxin Complex Provides Insights into Its Oral Toxicity

Botulinum neurotoxins (BoNTs) are produced by Clostridium botulinum and cause the fatal disease botulism, a flaccid paralysis of the muscle. BoNTs are released together with several auxiliary proteins as progenitor toxin complexes (PTCs) to become highly potent oral poisons. Here, we report the stru...

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Main Authors: Lee, Kwangkook, Gu, Shenyan, Jin, Lei, Le, Thi Tuc Nghi, Cheng, Luisa W., Strotmeier, Jasmin, Kruel, Anna Magdalena, Yao, Guorui, Perry, Kay, Rummel, Andreas, Jin, Rongsheng
格式: Artigo
語言:Inglês
出版: Public Library of Science 2013
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3795040/
https://ncbi.nlm.nih.gov/pubmed/24130488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003690
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