APP interacts with LRP4 and agrin to coordinate the development of the neuromuscular junction in mice

ApoE, ApoE receptors and APP cooperate in the pathogenesis of Alzheimer’s disease. Intriguingly, the ApoE receptor LRP4 and APP are also required for normal formation and function of the neuromuscular junction (NMJ). In this study, we show that APP interacts with LRP4, an obligate co-receptor for mu...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Choi, Hong Y, Liu, Yun, Tennert, Christian, Sugiura, Yoshie, Karakatsani, Andromachi, Kröger, Stephan, Johnson, Eric B, Hammer, Robert E, Lin, Weichun, Herz, Joachim
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: eLife Sciences Publications, Ltd 2013
Gaiak:
Developmental Biology and Stem Cells
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3748711/
https://ncbi.nlm.nih.gov/pubmed/23986861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.00220
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