APP interacts with LRP4 and agrin to coordinate the development of the neuromuscular junction in mice

ApoE, ApoE receptors and APP cooperate in the pathogenesis of Alzheimer’s disease. Intriguingly, the ApoE receptor LRP4 and APP are also required for normal formation and function of the neuromuscular junction (NMJ). In this study, we show that APP interacts with LRP4, an obligate co-receptor for mu...

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Bibliografski detalji
Glavni autori: Choi, Hong Y, Liu, Yun, Tennert, Christian, Sugiura, Yoshie, Karakatsani, Andromachi, Kröger, Stephan, Johnson, Eric B, Hammer, Robert E, Lin, Weichun, Herz, Joachim
Format: Artigo
Jezik:Inglês
Izdano: eLife Sciences Publications, Ltd 2013
Teme:
Developmental Biology and Stem Cells
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3748711/
https://ncbi.nlm.nih.gov/pubmed/23986861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.00220
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