APP interacts with LRP4 and agrin to coordinate the development of the neuromuscular junction in mice

ApoE, ApoE receptors and APP cooperate in the pathogenesis of Alzheimer’s disease. Intriguingly, the ApoE receptor LRP4 and APP are also required for normal formation and function of the neuromuscular junction (NMJ). In this study, we show that APP interacts with LRP4, an obligate co-receptor for mu...

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Detaylı Bibliyografya
Asıl Yazarlar: Choi, Hong Y, Liu, Yun, Tennert, Christian, Sugiura, Yoshie, Karakatsani, Andromachi, Kröger, Stephan, Johnson, Eric B, Hammer, Robert E, Lin, Weichun, Herz, Joachim
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: eLife Sciences Publications, Ltd 2013
Konular:
Developmental Biology and Stem Cells
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3748711/
https://ncbi.nlm.nih.gov/pubmed/23986861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.00220
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