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Evidence for Multiple Distinct Interactions between Hepatitis B Virus P Protein and Its Cognate RNA Encapsidation Signal during Initiation of Reverse Transcription

Replication of hepatitis B virus (HBV) via protein-primed reverse transcription is initiated by binding of the viral P protein to the conserved ε stem-loop on the pregenomic (pg) RNA. This triggers encapsidation of the complex and the ε-templated synthesis of a short P protein-linked DNA oligonucleo...

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Detalhes bibliográficos
Main Authors: Feng, Hui, Chen, Ping, Zhao, Fei, Nassal, Michael, Hu, Kanghong
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3748129/
https://ncbi.nlm.nih.gov/pubmed/23977352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0072798
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