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SELEX-derived aptamers of the duck hepatitis B virus RNA encapsidation signal distinguish critical and non-critical residues for productive initiation of reverse transcription

Protein-primed replication of hepatitis B viruses (HBVs) is initiated by the chaperone dependent binding of the reverse transcriptase (P protein) to the bulged ε stem-loop on the pregenomic RNA, and the ε-templated synthesis of the 5′ terminal nucleotides of the first DNA strand. How P protein recog...

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Autors principals: Hu, Kanghong, Beck, Jürgen, Nassal, Michael
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2004
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC514392/
https://ncbi.nlm.nih.gov/pubmed/15314208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkh772
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