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Stable T-bet(+)GATA-3(+) Th1/Th2 Hybrid Cells Arise In Vivo, Can Develop Directly from Naive Precursors, and Limit Immunopathologic Inflammation

Differentiated T helper (Th) cell lineages are thought to emerge from alternative cell fate decisions. However, recent studies indicated that differentiated Th cells can adopt mixed phenotypes during secondary immunological challenges. Here we show that natural primary immune responses against paras...

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Bibliografske podrobnosti
Main Authors: Peine, Michael, Rausch, Sebastian, Helmstetter, Caroline, Fröhlich, Anja, Hegazy, Ahmed N., Kühl, Anja A., Grevelding, Christoph G., Höfer, Thomas, Hartmann, Susanne, Löhning, Max
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2013
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Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3747991/
https://ncbi.nlm.nih.gov/pubmed/23976880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1001633
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